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New Clues Show How the Immune System Fights COVID

New Clues Show How the Immune System Fights COVID
By Brian Owens
May 13, 2021 When the immune system detects an invading virus like COVID-19, it sends swarms of antibodies to latch on to it, blocking its ability to attach to cells and marking it for destruction by other cells. Now, new research shows in striking detail how that process works in people who have successfully recovered from COVID-19 and offers new insights to help others.
So far, scientists have focused on one part of the coronavirus spike the receptor-binding domain which the virus uses to attach and gain access to human cells. This part of the coronavirus attaches directly to a person s cells to infect them, and is the part that researchers have made their top priority for vaccine and drug development. The monoclonal antibody therapies the FDA authorized last year use this same target. ....

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New Clues Show How the Immune System Fights COVID-19

New Clues Show How the Immune System Fights COVID-19
medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.

United States , Gregory Ippolito , Jason Lavinder , University Of Texas At Austin , Drug Administration , ஒன்றுபட்டது மாநிலங்களில் , கிரெகொரி இப்பொழித்தோ , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் ஆஸ்டின் ,

SARS-CoV-2 with Genomic Deletions Escapes an Antibody

SARS-CoV-2 with Genomic Deletions Escapes an Antibody
Researchers identify deletions in the N-terminal domain of the spike protein that allow the coronavirus to avoid antibody neutralization and that may contribute to the emergence of new variants.
Feb 16, 2021
ABOVE: Merged images illustrate multiple antibodies (green and red) binding to the wildtype SARS-CoV-2 spike protein, which is produced by human cells (DNA in blue, left). In cells (DNA in blue, right) that produce a version of the spike protein with deletions, some antibodies fail to bind (absence of green), while others (red) still attach well.
KEVIN MCCARTHY AND PAUL DUPREX
When SARS-CoV-2, the virus behind the COVID-19 pandemic, first emerged, scientists expected it to evolve slowly because the virus copies its big RNA genome with a polymerase that also corrects errors, thus minimizing the chance for certain types of mutations. This enzyme functionality isn’t present in other RNA viruses such as i ....

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