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Brain Tumors Incited by Blood Stem Cells

Brain Tumors Incited by Blood Stem Cells June 28, 2021 A positive link has been found between tumor-associated blood stem cells and glioblastoma progression. This link is supported by evidence from experiments in which blood stem cells were co-cultured with tumor organoids. (The fluorescently labeled tumor organoids in this image were grown from patient cells.) In these experiments, the blood stem cells were shown to promote glioblastoma cell proliferation and PD-L1 expression. [K. Stratmann and C. Dobersalske, German Cancer Research Center] Glioblastomas are more inclined to dig in and spread out if they are egged on by hematopoietic stem cells. To “dig in,” the glioblastomas become more immunosuppressive. To “spread out,” they support the proliferation of cancer cells, promoting malignancy. The connection between immunosuppressive/malignant glioblastomas and blood stem cells was discovered by scientists affiliated with the German Cancer Consortium (DKTK). These scientist

New Drug Effective Against Lung Cancers Caused by Common Genetic Error

Что было обещано Зеленским на прошлых пресс-конференциях

Что было обещано Зеленским на прошлых пресс-конференциях
news-front.info - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-front.info Daily Mail and Mail on Sunday newspapers.

Novel Antibody Shows Benefit in Cold Agglutinin Disease

Apr 8, 2021 Treatment increased hemoglobin, decreased fatigue Results from a small open-label trial suggested that treatment with an investigational humanized monoclonal antibody may be an effective treatment for cold agglutinin disease, a rare autoimmune hemolytic anemia for which there are no approved therapies. The 26-week, single-group trial tested intravenous sutimlimab in 24 cold agglutinin patients who had recently undergone transfusions and found infusions of the antibody halted hemolysis, increased hemoglobin levels, and reduced fatigue in more than half of patients. The composite primary endpoint was a “normalization of hemoglobin level to 12 g or more per deciliter or an increase in hemoglobin level of 2 g or more per deciliter from baseline, without red-cell transfusion or medications prohibited by protocol,” Alexander Röth, MD, of the West German Cancer Center, University Hospital Essen, University of Duisburg-Essen in Essen, Germany, and colleagues reported.

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