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Dazodalibep improves disease activity, symptoms in two Sjögren's syndrome populations

Dazodalibep has successfully improved disease activity and symptoms two patient populations with Sjögren’s syndrome in a phase 2 trial, according to a press release from Horizon Therapeutics. The company added that dazodalibep (VIB4920, Horizon), a CD40 ligand antagonist, is currently the only drug in development to achieve the primary endpoint in these populations in a phase 2 trial. ....

Frederickb Vivino , Shenaz Bagha , Elizabethhz Thompson , University Of Pennsylvania Perelman School Medicine , Penn Presbyterian Medical Center , Pennsylvania Perelman School , Syndrome Patient Reported Index ,