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'Very important': Belimumab decreases lupus flare vs placebo in early, established disease

Treatment with belimumab resulted in fewer flares in patients with either early or established systemic lupus erythematosus, especially among those with no baseline organ damage, according to data presented at the EULAR 2024 Congress.
“The benefits of early treatment of SLE for the prevention of repeated flares of disease activity, as well as the need to limit glucocorticoid exposure, are ....

United States , Byjustin Cooper , Shenaz Bagha , Karen Costenbader , Harvard Medical School , Lupus Erythematosus National , British Isles Lupus Assessment Group , North East Asia , Activity Index ,

FDA advisory committee backs donanemab for early-stage Alzheimer's

An FDA advisory panel on Monday voted in favor of donanemab as a treatment for early symptomatic Alzheimer’s disease.In a press conference on June 10, the Peripheral and Central Nervous System Drugs Advisory Committee ruled 11-0 that donanemab (Eli Lilly & Co.), a once-per-month, 30-minute infusion treatment, was effective in treating individuals with mild cognitive impairment and mild ....

United States , Cynthia Carlsson , Nilufer Ertekin Taner , Shenaz Bagha , Wisconsin Alzheimer Institute , Eli Lilly Co , Central Nervous System Drugs Advisory Committee , Eli Lilly , Mayo Clinic , Wisconsin Alzheimer ,

Lab results, symptom tracking top list of key metrics among rheumatology patients

The ability to view laboratory results, track symptoms and sharing them with a provider were rated as the most useful potential app functions by patients with rheumatic and musculoskeletal diseases, according to data.“As patient education continues to transition from paper to online resources, it is important to understand how education and other patient needs could be satisfied in a ....

New York , United States , Williamb Nowell , Byjustin Cooper , Shenaz Bagha , Excellence Network In Rheumatology , Global Healthy Living Foundation , Excellence Network ,

Targeted psoriatic arthritis therapies demonstrate low risk for serious infection

Serious infections were uncommon among patients with psoriatic arthritis exposed to targeted therapies for the first time in “a large and exhaustive” French cohort, according to data published in RMD Open.Compared with new users of adalimumab (Humira, Abbvie), risk for serious infection was significantly lower among new users of etanercept (Enbrel, Immunex) and ustekinumab (Stelara, ....

France General , Byjustin Cooper , Shenaz Bagha , University Paris , Eli Lilly Co , Val De Mame , Simponi Aria , Janssen Biotech , Eli Lilly ,

Uplizna reduces IgG4 related disease flare risk by 87% in MITIGATE trial

The monoclonal antibody Uplizna met key endpoints in a phase 3 trial for the treatment of IgG4-related disease, marking the first time a placebo-controlled study has shown benefit in the condition, according to a press release from Amgen.Topline results from the double-blind, randomized trial, called MITIGATE, demonstrated an 87% reduced risk for IgG4-related disease (IgG4-RD) flare in patients ....

United States , Jay Bradner , Shenaz Bagha , Zachary Wallace , Massachusetts General Hospital ,