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Significant Fatigue Common in Adult Patients with Sickle Cell Disease

A lower FACIT-Fatigue score, indicating higher fatigue was independently associated with female sex, a high BMI, a high stress level, and poor sleep quality.

Pegcetacoplan Contributes to Better Outcomes in PNH vs Other Treatments

An analysis of 2 phase 3 trials supporting the use of pegcetacoplan (PEG) in the treatment of paroxysmal nocturnal hemoglobinuria (PNH) assessed the benefits of this treatment compared with eculizumab (ECU) and supportive care measures.

Melatonin Fails to Ease Fatigue in Patients With Early-Stage Breast Cancer Undergoing Radiotherapy

Melatonin showed no benefit for cancer-related fatigue or other symptoms in women with early-stage breast cancer receiving radiotherapy treatment.

Iptacopan Demonstrates 38.3% Proteinuria Reduction in Patients With IgAN

Iptocopan demonstrated superiority when treating patients with immunoglobulin A nephropathy and is the first drug to specifically target the alternative complement pathway.

Dactylitis, enthesitis resolution linked to less pain, fatigue in guselkumab-treated PsA