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Early Olezarsen Results Show 50% Reduction in Triglycerides

A drug targeting mRNA essential for APO C-III production provided a 50% reduction in triglycerides in BRIDGE-TIMI 73a, the largest ever observed in a controlled trial. ....

United States , North Carolina , Daniel Soffer , Brian Bergmark , Nehaj Pagidipati , National Lipid Association , American College Of Cardiology , Duke Clinical Research Institute , Duke School Of Medicine , American College , Scientific Session , New England , Major Subgroup Failed , North America , Penn Medicine , National Lipid , Duke School , Ipid Management , Cv Risk , Cardiovascular Risk , V Risk Factors , Cardiovascular Risk Factors , Cardiovascular Risk Management , Hypertriglyceridemia Hypertriglyceridaemia , Liver Enzymes , Liver Studies ,

Alcohol-Related Liver Disease Mortality Higher in Women

Despite lower prevalence rates, women with steatotic liver disease related to alcohol consumption had close to double the risk of dying than men with the same condition. ....

United States , Los Angeles , Susan Cheng , Hongwei Ji , Us National Health , Qingdao University , Sinai Medical Center , Nutrition Examination Survey , Cedars Sinai Medical Center , Ipid Management , Liver Disease , Hepatic Impairment , High Density Lipoprotein Cholesterol , Fdl C , Vldl Cholesterol , Alcohol Use , Body Mass Index , Cardiometabolic Risk , Cardiometabolic Risk Factors , Practice Management ,

Light Activity in Childhood May Lower Cholesterol

Light physical activity may be a crucial intervention target to attenuate the risk for elevated lipid levels and their sequelae in the pediatric population, study said. ....

United Kingdom , Norra Savolax , Andrewo Agbaje , Institute Of Public Health , University Of Eastern Finland , School Of Medicine , Avon Longitudinal Study , Public Health , Clinical Nutrition , Eastern Finland , Clinical Endocrinology , Ipid Management , Physical Activity , Cv Risk , Cardiovascular Risk , V Risk Factors , Cardiovascular Risk Factors , Cardiovascular Risk Management , Uk Site Content United Kingdom , United Kingdom , High Density Lipoprotein Cholesterol , Fdl C , Vldl Cholesterol , Vldl Cholesterol ,

Higher Weight Loss on Tirzepatide Links to Seven Factors

Data from four tirzepatide pivotal trials in people with type 2 diabetes showed ≥15% weight loss in 25% of those on tirzepatide, with seven factors significantly linked with greater weight loss. ....

Eli Lilly , Novo Nordisk , Diabetes Mellitus Type 2 , Iabetes Mellitus Type Ii , Type 2 Diabetes , Weight Loss , Weight Management , Cardiometabolic Risk , Ipid Management , Liver Enzymes , Liver Studies , High Density Lipoprotein Cholesterol , Fdl C , Ndocrine System ,

Metabolic Effects of Estetrol for Postmenopausal Women

Participants taking estetrol experienced beneficial changes across a variety of metabolic measures, according to a new study presented at the Menopause Society. ....

United States , Wolf Utian , Chrisandra Shufelt , Case Western Reserve University , American Menopause Society , Medscape Professional Network , Menopause Society , North American Menopause Society , Health Research Center , Mayo Clinic Florida , Latin America , North America , Menopause Specific Quality , Clinical Global Impression , Medscape Professional , Menopausal Syndrome , Ipid Management , High Density Lipoprotein Cholesterol , Fdl C , Low Ldl Cholesterol , Ow Low Density Lipoprotein Cholesterol , Estrogen Therapy , Pain Management , Pain Management , Quality Of Life , Ealth Related Quality O ,