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POT1-mediated long telomere syndrome is associated with familial clonal hematopoiesis

1. In this retrospective study, carriers with mutations in the gene encoding the protection of telomeres 1 protein (POT1) were found to have elongated telomeres compared to non-carrier relatives. 2. POT1 gene mutations were associated with a predisposition to a familial clonal hematopoiesis syndrome, increasing the risk of several neoplasms. Evidence Rating Level: 2 (Good) ....

Minute Medicine Inc , Rating Level , Chronic Disease , Chronic Lymphocytic Leukemia , Clonal Hematopoiesis , Familial Clonal Hematopoiesis , Long Telomere Syndrome , Pot1 Mediated Long Telomere Syndrome ,

Breakthrough Cancer awards MD Anderson $5.7M for AML research

Breakthrough Cancer awards MD Anderson $5.7M for AML research
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Break Through Cancer funds AML research at MD Anderson

The University of Texas MD Anderson Cancer Center was awarded more than $5.7 million in grants from Break Through Cancer to support collaborative research teams working to discover novel molecular targets to eradicate minimal residual disease in acute myeloid leukemia (AML) and to treat clonal hematopoiesis, a precursor to AML. ....

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Prevent Cancer Foundation awards eight new research grants

Prevent Cancer Foundation awards eight new research grants
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Prevent Cancer Foundation awards eight new research grants

Prevent Cancer Foundation awards eight new research grants
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