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POT1-mediated long telomere syndrome is associated with familial clonal hematopoiesis

1. In this retrospective study, carriers with mutations in the gene encoding the protection of telomeres 1 protein (POT1) were found to have elongated telomeres compared to non-carrier relatives. 2. POT1 gene mutations were associated with a predisposition to a familial clonal hematopoiesis syndrome, increasing the risk of several neoplasms. Evidence Rating Level: 2 (Good) ....

Minute Medicine Inc , Rating Level , Chronic Disease , Chronic Lymphocytic Leukemia , Clonal Hematopoiesis , Familial Clonal Hematopoiesis , Long Telomere Syndrome , Pot1 Mediated Long Telomere Syndrome ,