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Novartis shares positive late-stage results for Fabhalta in rare kidney disease C3 glomerulopathy

Approximately one to two people per million worldwide are diagnosed with C3G every year ....

David Soergel , David Kavanagh , Newcastle University , European Medicines Agency , European Renal Association Congress , Drug Administration ,

Novartis: presented results for kidney disease

Novartis has presented the results of a pre-specified interim analysis of the Phase III ALIGN study of atrasentan, an investigational oral selective endothelin A receptor antagonist, in patients with. ....

David Soergel , Hiddo Heerspink , Metabolic Development , European Renal Association , Groningen University Medical Center , Professor Hiddo Heerspink , Global Head , Novartis Cardiovascular ,

Novartis releases Phase III data on its investigational oral therapy to treat chronic kidney disease

Novartis releases Phase III data on its investigational oral therapy to treat chronic kidney disease
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David Soergel , Bonnie Schneider , Igan Foundation , European Renal Association , Fe Mental Health Series How , Metabolism Development Unit , Health Series , Global Head ,

Novartis' atrasentan shows to reduce proteinuria in Phase III IgAN trial

Atrasentan’s safety profile in the trial was deemed favourable, aligning with previous data. ....

David Soergel , Metabolism Development Unit , Drug Administration , Clinical Trials Arena ,

Novartis presents latest Phase III Fabhalta® (iptacopan) data in C3 glomerulopathy (C3G) showing clinically meaningful and statistically significant 35.1% proteinuria reduction vs. placebo

Secondary endpoint data for estimated glomerular filtration rate (eGFR) showed numerical improvement over 6 months vs. placebo1; additional 6-month open-label. ....

Czech Republic , United States , Parag Mahanti , David Soergel , Prnewswire Novartis , Marianne Silkj , Marlena Abdinoor , Jonathan Graham , David Kavanagh , Sloan Simpson , Faculty Of Medical Sciences At Newcastle University , University Of Washington , G Steering Committee Member , Metabolism Development Unit , European Renal Association , Novartis Pharmaceuticals Corporation , Exchange Commission , Glomerular Diseases Work Group , Professor David Kavanagh , Complement Therapeutics , Honorary Consultant Nephrologist , Medical Sciences , Newcastle University , Steering Committee , Global Head , Parallel Group ,