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Age is just a number: Immune cell 'epigenetic clock' ticks independently of organism lifespan

Researchers use epigenetic clock, DNA methylation and mouse model to demonstrate that T cell proliferation can stretch past organism lifespan and acuta lymphoblastic leukemia T cells appear hundreds of years old. ....

Anoop Babu Vasandan , Caitlin Zebley , David Masopust , Andrew Soerens , Zhaoming Wang , April Mueller , Vaiva Vezys , Stephen Baylin , Charles Mullighan , Christopher Hiner , Ilaria Iacobucci , Harris Goldstein , Peter Jones , Ben Youngblood , Cure Foundation , University Of Minnesota , Jude Children Research Hospital , Jude Department Of Immunology , Alex Lemonade Stand Foundation , Van Andel Institute , National Institutes Of Health , Albert Einstein College Of Medicine , National Comprehensive Cancer Network , Jude Children , Research Hospital , Jude Department ,