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Trastuzumab Deruxtecan Effective For HR-Positive, HER2-Low Breast Cancer Treatment After Endocrine Therapy

Findings from ASCO 2024 suggest deruxtecan (T-DXd) may become a preferred first-line treatment for patients with hormone receptor (HR)-positive, HER2-low metastatic breast cancer that progressed after endocrine therapy. ....

United States , Erical Mayer , Caffreym Trastuzumab , Daiichi Sankyo , Giuseppe Curigliano , American Society Of Clinical Oncology , Dana Farber Cancer Institute , European Institute Of Oncology , Image Credit , American Society , Clinical Oncology , European Institute ,

Enhertu Boosts PFS in Pretreated, HR-Positive, HER2-Low and -Ultralow Breast Cancer

Enhertu lengthened the time to progression in patients with HR-positive, HER2-low or -ultralow metastatic breast cancer. ....

New Haven , United States , Giuseppe Curigliano , Ian Krop , European Institute Of Oncology , Clinical Sciences At Yale Cancer Center , University Of Milan , Clinical Trials Office , European Institute , Clinical Sciences , Yale Cancer Center ,

Antibody-Drug Conjugate Picks Up Another Win in HR+/HER2-low Breast Cancer

Trastuzumab deruxtecan extended its superiority versus chemotherapy into HER2-ultralow ....

United States , Julie Gralow , Giuseppe Curigliano , Charles Bankhead , Erica Mayer , American Society Of Clinical Oncology , European Institute Of Oncology , University Of Milan , European Institute , American Society , Clinical Oncology , Dana Farber Cancer , Medpage Today ,

Trastuzumab deruxtecan improves PFS in pretreated breast cancer

CHICAGO — Trastuzumab deruxtecan extended PFS compared with standard chemotherapy for certain patients with pretreated breast cancer, according to findings presented at ASCO Annual Meeting.The analysis — which included patients with hormone receptor-positive, HER2-low or HER2-ultralow metastatic breast cancer that progressed after endocrine therapy — also showed considerably ....

United States , Giuseppe Curigliano , Mindy Valcarcel , Daiichi Sankyo , Bymark Leiser , University Of Milan , European Institute Of Oncology , European Institute ,

ADCs for Breast Cancer: Clear Benefits, Manageable Risks

ADCs are rapidly changing the treatment landscape for patients with metastatic breast cancer, with the agents demonstrating improved efficacy and manageable risks. ....

Memorial Sloan Kettering Cancer Center , New York , United States , Soult Ukpyolsi , South Korea , Republic Of Korea , Bae Kim , Giuseppe Curigliano , Komal Jhaveri , European Society For Medical Oncology , University Of California San Francisco , University Of Milan , University Of Ulsan College Medicine , European Society , Medical Oncology , Breast Cancer , New York City , Medscape Medical News , Sung Bae Kim , Ulsan College , California San Francisco ,