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Bile Duct Cancer Continues to Respond to Zanidatamab, Per Longer Follow-Up

Zanidatamab continued to lead to responses and improved overall survival in pretreated HER2-positive biliary tract cancer. ....

United States , Department Of Gastrointestinal Medical Oncology , University Of Texas Md Anderson Cancer Center , Shubham Pant , Gastrointestinal Medical Oncology , Investigational Cancer Therapeutics , Phasei Center , Cancer Center ,

Zanidatamab exhibits 'promising' efficacy in advanced HER2-positive biliary tract cancer

CHICAGO — Zanidatamab exhibited durable antitumor activity among patients with previously treated advanced HER2-amplified biliary tract cancer, according to results of the phase 2B HERIZON-BTC-01 study presented at ASCO Annual Meeting.More than half of patients who received zanidatamb (Jazz Pharmaceuticals/Zymeworks) monotherapy survived at least a year and median OS exceeded 15 months. ....

United States , Bymark Leiser , Mindy Valcarcel , University Of Texas Md Anderson Cancer Center , Jazz Pharmaceuticals Zymeworks , Jazz Pharmaceuticals , Shubham Pant , Cancer Center ,

Jazz Pharmaceuticals Presents Overall Survival and Longer Follow-Up Data from HERIZON-BTC-01 Trial Evaluating Zanidatamab in Previously Treated HER2-Positive Biliary Tract Cancer at ASCO 2024

/PRNewswire/ Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced long-term follow-up results, including the first-ever overall survival (OS) findings,. ....

United States , Kristin Bhavnani , Mohamedtaki Abdulaziz Tejani , Hye Jin Choi , Jean Phillippe Metges , Nobuyoshi Hiraoka , Andrean Flynn , Rob Iannone , Asia Pacific , European Medicines Agency , Jazz Pharmaceuticals , Department Of Gastrointestinal Medical Oncology , Beigene Ltd , Exchange Commission , Commission File No , American Society Of Clinical Oncology , University Of Texas Md Anderson Cancer Center , Drug Administration , American Society , Clinical Oncology , Annual Meeting , Gastrointestinal Cancer , Shubham Pant , Gastrointestinal Medical Oncology , Investigational Cancer Therapeutics , Biologics License Application ,

Zanidatamab induces response in refractory HER2-positive biliary tract cancer

Zanidatamab induces response in refractory HER2-positive biliary tract cancer
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United States , Mindy Valcarcel , Bymark Leiser , Jazz Pharmaceuticals Zymeworks , University Of Texas Md Anderson Cancer Center , Shubham Pant , Cancer Center ,

KRAS inhibitors: The next frontier beckons

There has been several developments in the KRAS inhibitor space, shaping the KRAS inhibitors of the future. ....

United States , United Kingdom , Bristol Myers Squibb , Eli Lilly , Amgen Lumakras , University Of California San Francisco , European Laboratory Research Innovation Group , Md Anderson Cancer Center , Research Innovation , California San Francisco , Shubham Pant , Gastrointestinal Medical Oncology , Cancer Center , Molecular Therapeutics Research Program , Karmanos Cancer Institute , European Laboratory Research , Innovation Group , Jason Kettle , California Based Revolution Medicines , Prescription Drug User Fee Act , Massachusetts Based Elicio Therapeutics , Pharmaceutical Technology ,