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Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab. ....

United States , Brentl Wood , Susanm Obrien , Anjalis Advani , Aaront Gerds , Jeraldp Radich , Mark Litzow , Janel Liesveld , Matthew Wieduwilt , Anna Moseley , Harryp Erba , Los Angeles , Deepa Jeyakumar , George Yaghmour , Ceciliacs Yeung , Kristen Odwyer , Ehabl Atallah , Megan Othus , Elad Sharon , Uc Irvine Medical Center , Wilmot Cancer Institute , Cancer Research Network , Cleveland Clinic Cancer Institute , National Cancer Institute , Data Management Center , University Of Washington ,

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly
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United States , Mark Litzow , Matthew Wieduwilt , Ceciliacs Yeung , Ehabl Atallah , Anna Moseley , Susanm Obrien , Aaront Gerds , Megan Othus , Janel Liesveld , Brentl Wood , Harryp Erba , Anjalis Advani , Kristen Odwyer , Elad Sharon , Jeraldp Radich , Los Angeles , Deepa Jeyakumar , George Yaghmour , Cleveland Clinic Cancer Institute , Wilmot Cancer Institute , Amgen Inc , Data Management Center , National Cancer Institute Clinical Trials Network , Uc Irvine Medical Center , Cancer Research Network ,

New Graft Strategy May Improve Outcomes for Blood Stem Cell Recipients

Removing one type of T cell from donor blood used for stem cell grafts could greatly reduce a serious complication called graft-versus-host disease in ....

Warren Shlomchik , Fred Hutch , Stuart Seropian , Marie Bleakley , Melindaa Biernacki , Heather Persinger , Shelly Heimfeld , Stuart Isett , Barbara Hilzinger , Marye Flowers , Jenna Voutsinas , Stanleyr Riddell , Theodorea Gooley , Ann Dahlberg , Alison Sehgal , Keith Loeb , Brentl Wood , Paulj Martin , Leukemia Research At Fred Hutch , Yale School Of Medicine , Pittsburgh Foundation , University Of Pittsburgh School Medicine , Yale Cancer Center , University Of Washington , University Of Washington School Medicine , Hillman Cancer Center ,