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BLOG: CAR T-cells for long-term cure in pediatric ALL

Blogs | | Chimeric antigen receptor T-cell therapy targeting CD19 is highly effective for inducing remission among patients with relapsed or refractory B-cell acute lymphoblastic leukemia.Despite that, 50% of patients relapse after CAR-T therapy, and curative options for patients who relapse after CD19 CAR-T are limited, with no standard approach to cure. ....

Marie Bleakley , Muna Qayed , Byniralin Shah , Niralin Shah , Bymuna Qayed , Mark Leiser , Peach Bowl Inc , Peach Bowl Legacy Fund , Marrow Transplant Clinical Trials Network Symposium , Blood Disorders Center , Emory University , University Of Washington School Medicine , Aflac Cancer , Washington School , Pediatric Transplantation , Peach Bowl ,

Immunotherapy

Supercharging the body’s immune system to attack tumor cells holds tremendous promise. Your support is instrumental to making this frontier of cancer research possible. ....

Fred Hutch , E Donnall Thomas , Bone Marrow Transplant , Targetedt Cell Immunotherapy , T Cell Therapy , Marie Bleakley , Philipd Greenberg , Shivani Srivastava , Geoffrey Hill , Bezos Family Immunotherapy Clinic ,

Novel transplant approach improves the odds for leukemia patients

A team lead by Fred Hutch physician-scientist Dr. Marie Bleakley has shown it can dramatically reduce chronic GVHD, a common debilitating side effect of stem cell transplantation in leukemia patients, using magnets to remove “naïve T cells” from the mixture of blood cells from a donor that are to be transplanted into the patient. ....

Warren Shlomchik , Marie Bleakley , Leukemia Research At Fred Hutch , University Of Pittsburgh School Medicine , Fred Hutchinson Cancer Research Center , Gerdin Family Endowed , Leukemia Research , Pittsburgh School , Hematopoietic Transplantation , Acute Myeloid Leukemia , Peripheral Blood Stem Cells , Allogeneic Transplant , Hematopoietic Stem Cell Transplant , Cell And Gene Therapy , T Cell ,