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Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab.

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Long-term results show combination treatment that skips chemotherapy is effective for older patients with Ph+ ALL

Long-term results show combination treatment that skips chemotherapy is effective for older patients with Ph+ ALL
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Cancer-research-network
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Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly
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Ceciliacs-yeung
Ehabl-atallah
Anna-moseley
Susanm-obrien
Aaront-gerds
Megan-othus

First Prospective Study of TKI Ponatinib Shows Benefit in Ph+ALL

The study findings add new insights, but also raise new questions, about the best treatment approach for Philadelphia chromosome-positive acute lymphoblastic leukemia.

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France-general
France
Texas
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Massachusetts
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Drug combination without chemotherapy can be effective in treating older patients with Ph+ ALL

The combination of dasatinib, blinatumomab, and prednisone can be effective in treating older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who are not good candidates for intensive chemotherapy treatment.

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Philadelphia
Pennsylvania
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Anjalis-advani
Kristen-odwyer
Emily-henderson
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American-society-for-hematology
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Cancer-research-network

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