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Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab. ....

United States , Brentl Wood , Susanm Obrien , Anjalis Advani , Aaront Gerds , Jeraldp Radich , Mark Litzow , Janel Liesveld , Matthew Wieduwilt , Anna Moseley , Harryp Erba , Los Angeles , Deepa Jeyakumar , George Yaghmour , Ceciliacs Yeung , Kristen Odwyer , Ehabl Atallah , Megan Othus , Elad Sharon , Uc Irvine Medical Center , Wilmot Cancer Institute , Cancer Research Network , Cleveland Clinic Cancer Institute , National Cancer Institute , Data Management Center , University Of Washington ,

Studies Highlight Impacts of Applying New Technologies in Everyday Care

/PRNewswire/ Researchers report striking progress in the application of cutting-edge tools and treatments to address longstanding challenges in blood. ....

United States , Cleveland Clinic , University Of Hong Kong , Hong Kong General , Hong Kong , United Kingdom , Diego Marina , Andrew Srisuwananukorn , Harinder Gill , Oliver Shastri , Aaront Gerds , Icahn School Of Medicine At Mount Sinai , Bavarian Cancer Research Institute , Technology Commission , American Society Of Hematology , Friedrich Alexander University Of Erlangen , United Kingdom National Health Service , Pfizer United Kingdom Ltd , Cf San Diego Convention Center , Ab San Diego Convention Center , A San Diego Convention Center , Center Study , Technology Fund , Ohio State University Comprehensive Cancer Center , Case Western Reserve University , Rare Disease Team ,

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly
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United States , Mark Litzow , Matthew Wieduwilt , Ceciliacs Yeung , Ehabl Atallah , Anna Moseley , Susanm Obrien , Aaront Gerds , Megan Othus , Janel Liesveld , Brentl Wood , Harryp Erba , Anjalis Advani , Kristen Odwyer , Elad Sharon , Jeraldp Radich , Los Angeles , Deepa Jeyakumar , George Yaghmour , Cleveland Clinic Cancer Institute , Wilmot Cancer Institute , Amgen Inc , Data Management Center , National Cancer Institute Clinical Trials Network , Uc Irvine Medical Center , Cancer Research Network ,

Momelotinib Could Represent Pivotal New Treatment Option in Myelofibrosis

Aaron T. Gerds, MD, PhD, expands on the potential role of momelotinib in the treatment of patients with myelofibrosis who present with anemia, details the data from MOMENTUM, and explains what FDA approval of momelotinib could mean for the treatment of this patient population. ....

United States , Aaront Gerds , Developmental Therapeutics Program , Cleveland Clinic Taussig Cancer Institute , Department Of Hematology , Department Of Medicine , Case Comprehensive Cancer Center , Medical Oncology , Cleveland Clinic Taussig Cancer , Red Cross , Myeloproliferative Neoplasm , Cleveland Clinic ,

New Frontiers in the Targeted Treatment of Myelofibrosis

New Frontiers in the Targeted Treatment of Myelofibrosis
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United States , Wake Forest University , North Carolina , Winston Salem , Ruben Mesa , Geron Incyte , Aaront Gerds , Levine Cancer Institute Enterprise Service Line , Cleveland Clinic Taussig Cancer Institute , Wake Forest University School Of Medicine , Bristol Myers Squibb , Accreditation Council For Continuing Medical Education , Case Comprehensive Cancer Center , Atrium Health , Integrity Continuing Education Inc , Clinical Research , Integrity Continuing Education , Levine Cancer Institute , Enterprise Cancer Service , Vice President , Cancer Programs , Wake Forest University School , Continuing Education , Accreditation Council , Continuing Medical Education , Integrity Continuing ,