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Combination of dasatinib and blinatumomab offers effective treatment for older Ph+ ALL patients

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years on an alternate regimen of dasatinib and blinatumomab. ....

Philadelphia , Pennsylvania , United-states , American , Brentl-wood , Susanm-obrien , Anjalis-advani , Aaront-gerds , Jeraldp-radich , Mark-litzow , Janel-liesveld , Matthew-wieduwilt

Studies Highlight Impacts of Applying New Technologies in Everyday Care

/PRNewswire/ Researchers report striking progress in the application of cutting-edge tools and treatments to address longstanding challenges in blood. ....

China , Florida , United-states , Italy , Cleveland-clinic , Singapore , University-of-hong-kong , Hong-kong-general , Hong-kong , United-kingdom , American , Diego-marina

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly

Combo Treatment Sans Chemotherapy Effective for Ph+ ALL Elderly
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United-states , Philadelphia , Pennsylvania , American , Mark-litzow , Matthew-wieduwilt , Ceciliacs-yeung , Ehabl-atallah , Anna-moseley , Susanm-obrien , Aaront-gerds , Megan-othus

Momelotinib Could Represent Pivotal New Treatment Option in Myelofibrosis

Aaron T. Gerds, MD, PhD, expands on the potential role of momelotinib in the treatment of patients with myelofibrosis who present with anemia, details the data from MOMENTUM, and explains what FDA approval of momelotinib could mean for the treatment of this patient population. ....

Ohio , United-states , Cleveland , Aaront-gerds , Developmental-therapeutics-program , Cleveland-clinic-taussig-cancer-institute , Department-of-hematology , Department-of-medicine , Case-comprehensive-cancer-center , Medical-oncology , Cleveland-clinic-taussig-cancer

New Frontiers in the Targeted Treatment of Myelofibrosis

New Frontiers in the Targeted Treatment of Myelofibrosis
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Cleveland , Ohio , United-states , Wake-forest-university , North-carolina , Winston-salem , Ruben-mesa , Geron-incyte , Aaront-gerds , Genentech , Levine-cancer-institute-enterprise-service-line , Novartis