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Tumor microenvironment helps aggressive lymphomas


Date Time
Tumor microenvironment helps aggressive lymphomas
The environment surrounding the cancerous cells of a lymphoma tumor has a strong influence on the progression of these blood-cell cancers and their responses to therapies, according to a new study by Weill Cornell Medicine investigators.
Measuring this molecular and cellular environment, or “microenvironment,” appears to represent a new type of precision-medicine approach to lymphoma classification and treatment.
CoRus13/Creative Commons
Diffuse large B-cell lymphoma.
The team analyzed the patterns of gene activity in tumor samples taken from the lymph nodes of thousands of lymphoma patients. They found that the cells within these tumors, which include both cancer cells and healthy cells, produce molecules that collectively constitute a distinct microenvironment for the tumors, influencing their biology and growth. ....

United States , Weill Cornell , Jim Schnabel , Leandro Cerchietti , John Leonard , American Association For Cancer Research , Division Of Hematology , Weill Cornell Medicine , Creative Commons , Cancer Discovery , American Association , Edward Meyer Cancer Center , Giorgio Inghirami , Cornell University , Irna Sequencing , Patient Outcomes , Cancer Research , ஒன்றுபட்டது மாநிலங்களில் , வெயில் கார்னெல் , ஜிம் ஶ்ந்யாபெல் , ஜான் லியோனார்ட் , அமெரிக்கன் சங்கம் க்கு புற்றுநோய் ஆராய்ச்சி , பிரிவு ஆஃப் ஹீமாட்டாலஜி , வெயில் கார்னெல் மருந்து , படைப்பு காமன்ஸ் , புற்றுநோய் கண்டுபிடிப்பு ,

Dana-Farber Cancer Institute and Deerfield Management Launch Riverway Discoveries


Deerfield commits up to $130 million over 10 years to fund translational research at Dana-Farber
Dana-Farber Cancer Institute and Deerfield Management Company, a healthcare investment management firm focused on advancing healthcare through investment, information and philanthropy, have formed a major translational research partnership to accelerate the development of therapeutics and diagnostics for cancer. Deerfield has committed up to $130 million over the next 10 years to advance research at Dana-Farber and translate scientific discoveries with potential applications for patients.
Riverway Discoveries represents the first time Deerfield has created a second such partnership with one of its academic collaborators. In the first agreement, announced in 2018, Deerfield committed $80 million to create the Center for Protein Degradation at Dana-Farber. ....

Dana Farber , James Flynn , Laurieh Glimcher , Deerfield Management Company , Dana Farber Cancer Institute , Farber Cancer Institute , Protein Degradation , Dana Farber Cancer , Riverway Discoveries , Lesley Solomon , Senior Vice President , Chief Innovation Officer , Through Riverway Discoveries , Drug Development , Patient Care , Health Care , டானா ஃபார்‌பர் , ஜேம்ஸ் ஃப்லிந் , தீர்ப்பியல்ட் மேலாண்மை நிறுவனம் , டானா ஃபார்‌பர் புற்றுநோய் நிறுவனம் , ஃபார்‌பர் புற்றுநோய் நிறுவனம் , டானா ஃபார்‌பர் புற்றுநோய் , நதி பாதை கண்டுபிடிப்புகள் , லெஸ்லி சாலமன் , மூத்தவர் துணை ப்ரெஸிடெஂட் , தலைமை கண்டுபிடிப்பு அதிகாரி ,