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Study reveals unexpected mechanism of drug resistance in kidney cancer

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Center s Kidney Cancer Program sheds light. Published in the Proceedings of the National Academy of Sciences, the study "Unconventional Mechanism of Action and Resistance to Rapalogs in Renal Cancer" provides evidence for an unanticipated role for nontumor cells in mediating the therapeutic effects of rapalogs in kidney cancer. ....

Juan Yang , James Brugarolas , Brugarolas Lab , Kidney Cancer Program , Proceedings Of The National Academy Sciences , Division Of Hematology , Ut Southwestern Medical Center Kidney Cancer Program , Southwestern Medical Center , Haroldc Simmons Comprehensive Cancer Center , Southwestern Medical , Medical Center , National Academy , Internal Medicine , Comprehensive Cancer Center ,

CAR T-Cell Therapy vs Bispecific Antibodies: Picking an Approach in R/R DLBCL

Marie Hu, MD, discusses considerations for the use of CAR T-cell therapy and bispecific antibodies in relapsed/refractory diffuse large B-cell lymphoma. ....

United States , Joseph Maakaron , Division Of Hematology , University Of Minnesota Medical School In Minneapolis , Onclive State , Science Summit , Minnesota Medical School ,

Study reveals unexpected mechanism of drug resista

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwe ....

United States , Jiwoong Kim , Alana Christie , James Brugarolas , Robert Lewis Kirby , Jerry Knight Rymer , Vanina Toffessi Tcheuyap , Arijit Mal , Annette Brannon Rymer , Payal Kapur , Mylinh Nguyen , Ramesh Butti , Cancer Center Support Grant , Division Of Hematology , Senior Research Scientist , Kidney Cancer Program , Proceedings Of The National Academy Sciences , Brugarolas Lab , National Cancer Institute , Sherry Wigley Crow Cancer Research , Southwestern Medical Center , Haroldc Simmons Comprehensive Cancer Center , National Academy , Internal Medicine , Comprehensive Cancer Center , National Cancer Institute Specialized Program ,

Study reveals unexpected mechanism of drug resista

For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwe ....

United States , Ramesh Butti , Mylinh Nguyen , Payal Kapur , Annette Brannon Rymer , Vanina Toffessi Tcheuyap , Arijit Mal , Jerry Knight Rymer , Robert Lewis Kirby , James Brugarolas , Alana Christie , Jiwoong Kim , Haroldc Simmons Comprehensive Cancer Center , Southwestern Medical Center , Sherry Wigley Crow Cancer Research , National Cancer Institute , Proceedings Of The National Academy Sciences , Brugarolas Lab , Senior Research Scientist , Kidney Cancer Program , Division Of Hematology , Cancer Center Support Grant , National Academy , Internal Medicine , Comprehensive Cancer Center , National Cancer Institute Specialized Program ,

ASCO 2024: Treatment Outcomes for Patients with Ga68-PSMA-PET Prostate Cancer with or Without Conventional Imaging Correlates

ASCO 2024, Prostate Cancer, metastatic hormone-sensitive prostate cancer (mHSPC), Ga68-PSMA-PET, EA8191/INDICATE (NCT04423211). ....

United States , University Of Texas , Wadih Issa , Julian Chavarriaga , Postdoctoral Gu Oncology Research , American Society Of Clinical Oncology , Department Of Internal Medicine , University Of Texas Southwestern , Division Of Hematology , Society Of Urologic Oncology , University Of Toronto , Clinical Oncology , Poster Session , Genitourinary Cancer , Research Fellow , Internal Medicine , Texas Southwestern , Urologic Oncology , Clinical Fellow ,