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Bio-Rad Announces Life Science Group Management Changes

Bio-Rad Laboratories, Inc. , a global leader in life science research and clinical diagnostics products, today announced the promotion of James J. Barry, currently Senior Vice President of Global. ....

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LRH Cuts Ribbon For High-tech Upgrade

Littleton Regional Healthcare (LRH) hosted a ribbon-cutting ceremony on April 18 for its laboratory automation system, featuring state-of-the-art chemistry and hematology analytical instruments. The full system went live early this ....

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Prueba rápida 12 drogas Multi-Drug (AMP,BAR,BZO,COC,THC,MTD,MET,MOP,OPI,PCP,TCA,TML) x 25 Panels • Wondfo • Biosystems, test drogas

RELIABLE: CLIA Waived for home or over-the-counter (OTC) use. Same technology used as Lab screening test. Results are accepted in most professional ....

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Antisense oligonucleotide therapeutic approach for Timothy syndrome

Timothy syndrome (TS) is a severe, multisystem disorder characterized by autism, epilepsy, long-QT syndrome and other neuropsychiatric conditions1. TS type 1 (TS1) is caused by a gain-of-function variant in the alternatively spliced and developmentally enriched CACNA1C exon 8A, as opposed to its counterpart exon 8. We previously uncovered several phenotypes in neurons derived from patients with TS1, including delayed channel inactivation, prolonged depolarization-induced calcium rise, impaired interneuron migration, activity-dependent dendrite retraction and an unanticipated persistent expression of exon 8A2–6. We reasoned that switching CACNA1C exon utilization from 8A to 8 would represent a potential therapeutic strategy. Here we developed antisense oligonucleotides (ASOs) to effectively decrease the inclusion of exon 8A in human cells both in vitro and, following transplantation, in vivo. We discovered that the ASO-mediated switch from exon ....

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Danaher shares jump 7% as the turnaround in biotech finally arrives

There was much more to like in this print, including strong headline results on the back of strength in all key operating segments. ....

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