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FDA Approves Elranatamab for Multiple Myeloma

Elranatamab is an off-the-shelf, B-cell maturation antigen CD3-targeted bispecific antibody. ....

Drug Administration , Priority Review , Breakthrough Therapy Designation , Risk Evaluation , Mitigation Strategy , Multiple Myeloma , Plasma Cell Myeloma , Biologic Therapy , Us Food And Drug Administration , Nited States Food And Drug Administration , Monoclonal Antibody , Proteasome Inhibitor , Risk Evaluation And Mitigation Strategies Rems , Patient Safety , Practice Management ,

SJS/TEN: Study Addresses Issues in Identifying Culprit Drug

In the absence of a lab test, identifying culprit drugs in patients with SJS/TEN is difficult, and patients take on average six medications at the time of their reaction, the authors of a new study write. ....

United States , George Washington University Hospital , District Of Columbia , Christine Ko , Karl Saardi , Sherriej Divito , Yale University , Drug Causality , Epidermal Necrolysis , Massachusetts General Hospital , New Haven , Skin And Soft Tissue Infection , Stevens Johnson Syndrome , Patient Safety , Fixed Drug Eruption , Human Leukocyte Antigen , La Human Leukocyte Antigen , Drug Induced Cutaneous Eruptions , Inpatient Care , Medical Records , Social Determinants Of Health ,

CAR T-Cell Therapy May Treat Antisynthetase Syndrome

In a case study, a patient with refractory antisynthetase syndrome with progressive myositis and interstitial lung disease showed significant improvement in 8 months after CAR T-cell therapy. ....

Bristol Myers Squibb , Ann Christin Pecher , University Hospital Tu , Physician Global Assessment , Christin Pecher , Biologic Therapy , Chimeric Antigen Receptort Cell Therapy , Chimeric Antigen Receptors , Himeric Immunoreceptors , Himerict Cell Receptors , Rtificialt Cell Receptors , Ar T , Interstitial Lung Disease , Systemic Lupus Erythematosus ,

Advances in HIV Vaccine Research Show Promise for Prevention

In their search for an effective HIV vaccine, researchers have explored several platforms and targets to generate a robust immune response. ....

Hiv Infection , Hiv Vaccine , Drug Development , Experimental Drug , Biologic Therapy , Cellular Mechanisms , Clinical Research , Clinical Trials , Linical Studies , Social Determinants Of Health , 019 Novel Coronavirus , 019 Ncov , Uhan Coronavirus , Uman Coronavirus Hku1 , Uman Coronavirus Oc43 , Cov Oc43 ,

CAR T-Cell Benefit in Lenalidomide-Refractory Myeloma

The CAR T-cell construct was associated with significantly better progression-free survival than standard-of-care multidrug regimens. ....

United States , Lenalidomide Revlimid , Myeloma International Staging System , American Society Of Clinical Oncology , Drug Administration , American Society , Clinical Oncology , New England Journal , Medscape Medical News , Multiple Myeloma International Staging System , Legend Biotech , Multiple Myeloma , Plasma Cell Myeloma , Biologic Therapy , Chimeric Antigen Receptort Cell Therapy , Chimeric Antigen Receptors , Himeric Immunoreceptors , Himerict Cell Receptors , Rtificialt Cell Receptors , Ar T , Alignant Neoplasia , Proteasome Inhibitor , Quality Of Life , Ealth Related Quality Of Life ,