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Finding culprit drug challenging in Stevens-Johnson syndrome/toxic epidermal necrolysis

Physicians must change their approaches to finding culprit drugs when treating Stevens-Johnson syndrome/toxic epidermal necrolysis, according to a study.Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a severe mucocutaneous desquamative disease that is almost always triggered by certain medications, Dayan J. Li, MD, PhD, of the department of dermatology at the Brigham and ....

Dayanj Li , Drug Causality , Epidermal Necrolysis ,

SJS/TEN: Study Addresses Issues in Identifying Culprit Drug

In the absence of a lab test, identifying culprit drugs in patients with SJS/TEN is difficult, and patients take on average six medications at the time of their reaction, the authors of a new study write. ....

United States , George Washington University Hospital , District Of Columbia , Christine Ko , Karl Saardi , Sherriej Divito , Yale University , Drug Causality , Epidermal Necrolysis , Massachusetts General Hospital , New Haven , Skin And Soft Tissue Infection , Stevens Johnson Syndrome , Patient Safety , Fixed Drug Eruption , Human Leukocyte Antigen , La Human Leukocyte Antigen , Drug Induced Cutaneous Eruptions , Inpatient Care , Medical Records , Social Determinants Of Health ,