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The U.S. Food and Drug Administration said on Thursday cancer therapies that use CAR-T technology will require changes to the so-called "boxed warning" to highlight the. ....
Despite concerns about the development of secondary T-cell malignancies due to CAR T-cell immunotherapy, experts still believed that the benefits outweigh the risks. ....
Infections, cardiopulmonary disease, and second cancers were among the leading causes of nonrelapse deaths in patients receiving CAR T-cell therapy, both in clinical trials and clinical practice. ....