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Upregulated expression of many LY6 genes linked to poor survival in endometrial cancer patients

A new research paper was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma." ....

Emily Henderson , Lukea Rathbun , Anthonym Magliocco , Villanova University , Ene Expression ,

LY6 gene family: Potential Tumor Antigens and Biomarkers in Endometrial Cancer

LY6 gene family: Potential Tumor Antigens and Biomarkers in Endometrial Cancer
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Lukea Rathbun , Anthonym Magliocco , Villanova University , Oncotarget Volume ,

Triple chemotherapy combination improves metastatic colorectal cancer outcomes


Credit: SWOG Cancer Research Network
Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination - of irinotecan, cetuximab, and vemurafenib - is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab.
Results of the SWOG study, led by Scott Kopetz, MD, PhD, of M.D. Anderson Cancer Center, are published in the
Journal of Clinical Oncology. The findings are expected to change the standard of care for patients with colorectal cancer that is metastatic - when tumors spread to other parts of the body - and includes a mutation in the BRAF gene called V600E. This mutation is found in about 10 percent of metastatic colorectal cancers and tumors with the mutation rarely responds to treatment, r ....

Howards Hochster , Katherinea Guthrie , Kanwalp Raghav , Yibing Yan , Chloee Atreya , Vank Morris , Dipen Maru , Alexey Sorokin , Heinz Josef Lenz , Anthonym Magliocco , Stephene Wang , Scott Kopetz , David Hong , Luisa Diaz , Shannonl Mcdonough , Richard Lanman , Carmen Allegra , Philipa Philip , Ganiraju Manyam , Guardant Health , European Society Of Medical Oncology , National Cancer Institute , Rutgers Cancer Institute Of New Jersey , Hope Foundation For Cancer Research , Cancer Research Network , University Of Colorado Denver ,