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'Disappointing' results question the utility of liquid biopsy-guided cancer treatment healio.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from healio.com Daily Mail and Mail on Sunday newspapers.
Credit: Correspondence to - Van K. Morris - [email protected] CEA as a blood-based biomarker in anal cancer which reported that the mean Carcinoembryonic Antigen (CEA) among subgroups by clinical status at the time of presentation to our institution was highest among those patients with metastatic Squamous cell carcinoma of the anal canal (SCCA) to visceral organs, however this finding was not statistically significant by ANOVA . By clinical subgroup, the percentage of patients with an abnormally elevated CEA was highest in those patients with metastatic disease to lymph nodes followed by recurrent/unresectable SCCA , and metastatic SCCA to visceral organs, and was statistically significant between groups. ....
Credit: SWOG Cancer Research Network Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination - of irinotecan, cetuximab, and vemurafenib - is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab. Results of the SWOG study, led by Scott Kopetz, MD, PhD, of M.D. Anderson Cancer Center, are published in the Journal of Clinical Oncology. The findings are expected to change the standard of care for patients with colorectal cancer that is metastatic - when tumors spread to other parts of the body - and includes a mutation in the BRAF gene called V600E. This mutation is found in about 10 percent of metastatic colorectal cancers and tumors with the mutation rarely responds to treatment, r ....