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Engineered bacteria deliver synthetic targets to solid tumors

For several years, researchers have been successfully using chimeric antigen receptor (CAR) T cells to target specific antigens found on blood cells as a cure for patients with leukemia and lymphoma. ....

Nicholas Arpaia , Rosa Vincent , Megan Craig , Herbert Irving Comprehensive Cancer Center , Columbia Vagelos College Of Physicians , Data Science Institute , Columbia Engineering , Tal Danino , Data Science , Vagelos College , Ancer Immunotherapy , Chimeric Antigen Receptor ,

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

In a recent review published in Immunity, researchers reviewed tumor-immunity cycle data. ....

Alpha Tauri , Ancer Immunotherapy , Ell Death , T Lymphocyte ,

Smart Immune Showcases Data and Presentations at ESGCT

PARIS, France, 12 October 2023 – Smart Immune, a clinical-stage biotechnology company developing ProTcell, a thymus-empowered T-cell progenitor therapy platform to fully and rapidly re-arm the immune system, announced today a series of activities in and around the European Society of Gene and Cell Therapy (ESGCT) 30th Annual Congress being held in Brussels, Belgium from October 24-27, 2023. Oral presentation by CSO ‘CAR ProTcell, towards well-tolerated and persistent off-the-shelf allogeneic CAR ....

Bruxelles Capitale , France General , Olivier Negre , Marina Cavazzana , Karine Rossignol , Chiara Bonini , Iordanis Arzimanoglou , Frank Staal , European Society Of Gene , University Vita , Leiden University Medical Center , European Innovation Council , Strategic Clinical Development Advisor , Smart Immune , European Society , Cell Therapy , Annual Congress , Chief Scientific Officer , University Vita Salute San Raffaele , San Raffaele , Scientific Advisory , Gene Therapy , Program Manager , European Innovation , Chief Executive Officer Karine Rossignol , Chief Executive Officer ,

Liquid biopsies could be used as an early marker of immunotherapy response, study finds

Liquid biopsies are blood tests that can serially measure circulating tumor DNA (cell-free DNA that is shed into the bloodstream by dying cancer cells). ....

United Kingdom , New York , United States , Megan Craig , Noushin Niknafs , Mark Sausen , Archana Balan , Benjamin Levy , Johns Hopkins , Julie Brahmer , Valsamo Elsa Anagnostou , Astra Zeneca , Bristol Myers Squibb , Jay Campbell , Johns Hopkins Kimmel Cancer Center , Us National Institutes Of Health , Commonwealth Foundation , Bloomberg Kimmel Institute For Cancer Immunotherapy , Juravinski Cancer Centre , Ottawa Hospital Research Institute , Canadian Cancer Society , Johns Hopkins University , Kingston Health Sciences Centre , Mark Foundation For Cancer Research , Princess Margaret Cancer Centre , Lung Cancer Precision Medicine Center ,

Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center. ....

Lily Ramsey , Johns Hopkins , Suzanne Topalian , Kellie Smith , Patrick Forde , Mark Yarchoan , Johns Hopkins Kimmel Cancer Center , Johns Hopkins Melanoma Skin Cancer Program , Bloomberg Kimmel Institute For Cancer Immunotherapy , Kimmel Institute , Johns Hopkins Kimmel Cancer , Skin Cancer Program , Cancer Cell , Drew Pardoll , Leisha Emens , Breast Cancer , Ancer Immunotherapy , Lung Cancer ,