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Review Highlights Potential of Neoadjuvant Immune Checkpoint Inhibition in Multiple Cancers

Recent evidence suggests that neoadjuvant immunotherapy offers a unique opportunity to explore disease mechanisms and identify new biomarkers of immune checkpoint blockade response and resistance, according to the researchers. ....

Suzanne Topalian , Bloomberg Kimmel Institute For Cancer Immunotherapy , Johns Hopkins Kimmel Cancer Center , Johns Hopkins Melanoma Skin Cancer Program , Cancer Cell , Kimmel Institute , Johns Hopkins , Skin Cancer Program , Immune Checkpoint Inhibitors , Immune Checkpoint Blockade ,

Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center. ....

Lily Ramsey , Johns Hopkins , Suzanne Topalian , Kellie Smith , Patrick Forde , Mark Yarchoan , Johns Hopkins Kimmel Cancer Center , Johns Hopkins Melanoma Skin Cancer Program , Bloomberg Kimmel Institute For Cancer Immunotherapy , Kimmel Institute , Johns Hopkins Kimmel Cancer , Skin Cancer Program , Cancer Cell , Drew Pardoll , Leisha Emens , Breast Cancer , Ancer Immunotherapy , Lung Cancer ,

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study
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Suzannel Topalian , Suzanne Topalian , Johns Hopkins Melanoma Skin Cancer Program , Bloomberg Kimmel Institute For Cancer Immunotherapy , Johns Hopkins Kimmel Cancer Center , Kimmel Institute , Johns Hopkins Kimmel Cancer , Johns Hopkins , Skin Cancer Program , Cancer Cell ,