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Deciphering progesterone's mechanisms of action in breast cancer

Deciphering progesterone's mechanisms of action in breast cancer
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Rajendraa Badwe , Sudeep Gupta , Mukuls Godbole , Amit Dutt , Suhail Ahmad , Gaurav Chakravorty , Homi Bhabha National Institute , Tata Memorial Centre , World Peace University , Peace University ,

New research sheds light on role of progesterone in breast cancer

A new research perspective was published in Oncotarget's Volume 14 on July 1, 2023, entitled, "Deciphering the mechanisms of action of progesterone in breast cancer." ....

Danielle Ellis , Rajendraa Badwe , Suhail Ahmad , Sudeep Gupta , Mukuls Godbole , Amit Dutt , Gaurav Chakravorty , Tata Memorial Centre , World Peace University , Homi Bhabha National Institute , Peace University , Breast Cancer ,

Precision Oncology Company 4baseCare launches one-of-its-kind Indian Population Specific Cancer Gene Panel

Study: Lung squamous patients harboring druggable mutations have lower median overall survival


Study: Lung squamous patients harboring druggable mutations have lower median overall survival
Oncotarget published
Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations which reported that unlike lung adenocarcinoma patients, there is no FDA-approved targeted-therapy likely to benefit lung squamous cell carcinoma patients.
The authors performed survival analyses of lung squamous cell carcinoma patients harboring therapeutically relevant alterations identified by whole exome sequencing and mass spectrometry-based validation across 430 lung squamous tumors.
They report a mean of 11.6 mutations/Mb with a characteristic smoking signature along with mutations in TP53, CDKN2A, NFE2L2, FAT1, KMT2C, LRP1B, FGFR1, PTEN and PREX2 among lung squamous cell carcinoma patients of Indian descent. ....

Amit Dutt , Kumar Prabhash , Emily Henderson , Oncotarget Research Output , Dutt Prabhash Research Team , Prabhash Research Team , Squamous Cell Carcinoma , Exome Sequencing , Lung Cancer , Mass Spectrometry , அமித் தத் , குமார் பிரபாஷ் , எமிலி ஹென்டர்சன் , பிரபாஷ் ஆராய்ச்சி அணி ,