Current HFA-ESC guidelines for diuretics in acute heart failure led to significant increases in natriuresis and diuresis over 2 days compared with usual care, in ENACT-HF.
It may seem counterintuitive, but a new trial testing extra sodium intake in patients receiving high-dose IV diuretics for acute HF challenges routine use of salt restriction in that setting.
Results of a new TOPCAT analysis point to the need to determine the optimal salt restriction range for patients with heart failure with preserved ejection fraction.