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Aficamten improves oxygen uptake in patients with obstructive hypertrophic cardiomyopathy

1. In this randomized controlled trial, aficamten significantly improved peak oxygen uptake in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM) compared with placebo. 2. The results for all 10 secondary endpoints were significantly improved with aficamten. Evidence Rating Level: 1 (Excellent) Study Rundown: HCM is one of the most common genetic heart diseases and is

Minute medicine incYork heart associationRating levelQuantitative understandingObstruction impactKansas city cardiomyopathy questionnaireNew york heart association

BridgeBio Pharma : BBIO – Acoramidis AG10 TTR – ISA 2024 – Acoramidis treatment related increase in serum TTR is associated with lower cardiovascular mortality in ATTR CM

Treatment-Related Early Increase in Serum TTR is Associated With Lower Cardiovascular Mortality in ATTR-CM: Insights From ATTRibute-CM Amrut.

United statesUnited kingdomNew yorkCzech republicUniversity collegeNew south walesUniversity of chicagoSan franciscoRegion flamandeSouth australiaSanta monicaUniversity of texas southwestern medical centerCity ofRichard wrightMatthias dupontSatish rao

BridgeBio Pharma : BBIO – Acoramidis AG10 TTR – ISA 2024 – Early increase in serum transthyretin level is an independent predictor of improved survival in ATTR cardiomyopathy

Early Increase in Serum Transthyretin Level Is an Independent Predictor of Improved Survival in ATTR Cardiomyopathy: Insights From Acoramidis Phase 3 Study ATTRibute-CM .

San franciscoUnited statesNoord hollandNew yorkUniversity of chicagoColumbia universitySteen hvitfeldt poulsenBrian adamKuma sinhaSurendhar reddy chepyalaAnique ducharmeSatish raoMathews maurerAmrut ambardekarMartha groganNitasha sarswat

BridgeBio Pharma : BBIO – Acoramidis AG10 TTR – ISA 2024 – Higher risk of mortality in previously hospitalized patients

Higher Risk of Mortality in Previously Hospitalized Patients: Insights From ATTRibute-CM Ahmad Masri1, Michele Emdin2, Keyur Shah3, Kunal Bhatt4,.

United statesSan franciscoPalo altoWestern australiaStanford universityDariusz korczykKunal bhattMichel khouriKevin alexanderJonathanc foxNoel dasguptaAhmad masriMichele emdinMartha groganMichael johnstoneSuresh siddhanti

Heart Failure Patients Who Do Yoga Have Stronger Hearts and Can be More Active

Heart Failure Patients Who Do Yoga Have Stronger Hearts and Can be More Active
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New yorkUnited statesAjit singhYork heart associationEuropean society of cardiologyDepartment of yogaIndian council of medical researchManipal academy of higher educationHeart failureEuropean societyIndian councilMedical researchManipal academyHigher educationKasturba hospitalNew york heart association