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 E-Mail IMAGE: Gladstone scientists uncover evidence that neurons are more sensitive to degeneration when they contain high levels of the protein apoE, which is associated with a higher risk of developing Alzheimer s. view more  Credit: Photo: Michael Short/Gladstone Institutes SAN FRANCISCO, CA May 6, 2021 In the brain of a person with Alzheimer s disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally. Some types of neurons in certain brain regions are more susceptible, and even among those subtypes mysteriously some perish and some do not. Researchers at Gladstone Institutes have uncovered molecular clues that help explain what makes some neurons more susceptible than others in Alzheimer s disease. In a study published in the journal

Kelly zalocuskyYanxia haoDavida bennettSeo yeon yoonNicole koutsodendrisAntara raoOlga cisne thomsonYadong huangAlicel taubesQin xuRamsey najmMaxiner nelsonRush university medical centerNational institutes of healthGladstone institutesNature neuroscience