Genetic risk scores not useful in predicting disease sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
University College London researchers found commercially available genetic tests only identified just 11 per cent of individuals who went on to develop disease, such as cancer.
<p>The new study, published in <em>BMJ Medicine</em>, looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not develop the disease test positive. Unaffected people usually outnumber those affected which results in far more false than true positive predictions.</p>