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Genetic risk scores do not have a place in public health screening

Researchers said the scoring system led to false positives and ‘performed poorly when predicting if a person would develop common diseases.

United kingdomCity ofAroon hingoraniNick waldMichael inouyeSam lambertJasmine grattonNicholas waldDusko ilicNational institute for healthInstitute of cardiovascular scienceBiomedical research centreInstitute of health informaticsBritish heart foundationUnited kingdom researchCare research

Over the counter genetic tests that claim to predict the risk of illnesses such as heart disease and cancer miss nine in ten cases

University College London researchers found commercially available genetic tests only identified just 11 per cent of individuals who went on to develop disease, such as cancer.

United kingdomSam lambertAroon hingoraniJasmine grattonMichael inouyeCambridge universityInstitute of health informaticsUniversity college londonInstitute of cardiovascular scienceCardiovascular scienceProfessor sir nicholas waldHealth informaticsProfessor michael inouyeProfessor sam lambert

Genetic risk scores do not have a place in public health screening | East London and West Essex Guardian Series

Researchers said the scoring system led to false positives and ‘performed poorly’ when predicting if a person would develop common diseases.

City ofUnited kingdomJasmine grattonAroon hingoraniMichael inouyeDusko ilicNicholas waldNick waldSam lambertBiomedical research centreCare researchInstitute of health informaticsUniversity of cambridgeUnited kingdom researchUniversity college londonBritish heart foundation

Genetic risk scores not useful in predicting disease, study argues

Genetic risk scores not useful in predicting disease, study argues
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Aroon hingoraniNick waldOur future healthUniversity college londonInstitute of health informaticsInstitute of cardiovascular scienceFuture healthProfessor aroon hingoraniCardiovascular sciencePolygenic score catalogProfessor sir nicholas waldHealth informaticsJasmine grattonSir nick wald

Genetic risk scores do not have a place in public health screening

Researchers said the scoring system led to false positives and ‘performed poorly’ when predicting if a person would develop common diseases.

United kingdomCity ofNick waldDusko ilicMichael inouyeJasmine grattonAroon hingoraniSam lambertNicholas waldInstitute of health informaticsCare researchUnited kingdom researchUniversity college londonUniversity of cambridgeBiomedical research centreNational institute for health