Scientists at the University of Dundee have reported a major breakthrough in targeting the causes of many diseases, using a `kiss of death' to destroy proteins which had previously been regarded as `undruggable'.
The University of Dundee’s Centre for Targeted Protein Degradation CeTPD is contributing in a global effort to explore new means of tackling solid tumours in children. Click to read more.
New class of intramolecular bivalent glue could transform cancer drug discovery phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.
A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.
Research led by Professor Alessio Ciulli at the University of Dundee’s recently opened Centre for Targeted Protein Degradation (CeTPD) has unlocked a class of proteins known as suppressor of cytokine signalling (SOCS), using a newly designed molecule that is able to target and bind to a protein class previously considered undruggable by using a masking technique to enter the cell. Click to read more.