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A major breakthrough in targeting the causes of many diseases - proteins

Scientists at the University of Dundee have reported a major breakthrough in targeting the causes of many diseases, using a `kiss of death' to destroy proteins which had previously been regarded as `undruggable'.

Masking technique strategy targets proteins

Research led by Professor Alessio Ciulli at the University of Dundee’s recently opened Centre for Targeted Protein Degradation (CeTPD) has unlocked a class of proteins known as suppressor of cytokine signalling (SOCS), using a newly designed molecule that is able to target and bind to a protein class previously considered undruggable by using a masking technique to enter the cell. Click to read more.

Ground-breaking drug discovery research centre opens at Dundee

The University of Dundee has today (Oct 26, 2023) celebrated the official opening of its multi-million pound Centre for Targeted Protein Degradation (CeTPD), by UK Science Minister George Freeman who met researchers behind pioneering studies of potential ways to treat diseases previously thought to be undruggable. Click to read more.

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