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Tenecteplase is equivalent to placebo between 4 5 and 24 hours after stroke onset

1. In this randomized controlled trial, tenecteplase administered at 4.5 to 24 hours after stroke onset to patients with an occluded middle cerebral artery (MCA) or internal carotid artery (ICA) was not superior to placebo. 2. Tenecteplase did not differ from placebo with regards to rates of death and symptomatic intracranial hemorrhage. Evidence Rating Level:

Minute medicine incRating levelConfidence interval

#VisualAbstract: Enfortumab Vedotin and Pembrolizumab Reduces Mortality in Metastatic Urothelial Carcinoma

Click here to read this study in The New England Journal of Medicine. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by

Minute medicine incAdvanced urothelial carcinoma

Seladelpar improves symptoms of primary biliary cholangitis

1. In this randomized controlled trial, among patients with primary biliary cholangitis (PBC) who had had inadequate response to ursodeoxycholic acid, seladelpar was superior to placebo in achieving biochemical response and symptomatic management. 2. Seladelpar had an acceptable safety profile, with similar rates of adverse events to a placebo. Evidence Rating Level: 1 (Excellent) Study

Minute medicine incRating levelConfidence intervalChronic diseasePrimary biliary cholangitisUrsodeoxycholic acid

Wellness Check: Spirituality | 2 Minute Medicine

Older adults who lose a child feared life collapse and utilized three main strategies for coping 1. The main concern of older adults after losing their child was fear of life collapse, which can be attributed to contextual factors of double suffering and the inefficiency of government support systems. 2. To cope with the death

Minute medicine incRating levelUmbrella review

#VisualAbstract: Benralizumab is noninferior to mepolizumab for treatment of eosinophilic granulomatosis with polyangitis

#VisualAbstract: Benralizumab is noninferior to mepolizumab for treatment of eosinophilic granulomatosis with polyangitis
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