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Hansen awarded prestigious Pew-Stewart Grant for Cancer Research

Hansen awarded prestigious Pew-Stewart Grant for Cancer Research
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Robert tjianErin osheaXavier darzacqAnders sejr hansenDepartment of biological engineeringPew stewart programMargaret stewartPew stewart scholars program for cancer researchPew stewart scholars in cancer research programPew scholars programLeilay mathers charitable foundationHarvard universityUniversity of california at berkeleyHansen labPew stewart scholar for cancer researchOxford university

Anders Sejr Hansen awarded prestigious Pew-Stewart Grant for Cancer Research

Anders Sejr Hansen awarded prestigious Pew-Stewart Grant for Cancer Research
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Study reveals recipe for even more powerful COVID-19 vaccines

Study reveals recipe for even more powerful COVID-19 vaccines
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Boston universityUnited statesHarvard universityShira weingarten gabbayPardis sabetiHasahn conwayMohsan saeedBroad instituteBu school of medicineNational institute of healthNational cancer instituteRagon instituteNational institute of allergyCancer research institute hearstBawd foundationLeadership program fellowship

New recipe could lead to better COVID-19 vaccines

New recipe could lead to better COVID-19 vaccines
futurity.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from futurity.org Daily Mail and Mail on Sunday newspapers.

Boston universityUnited statesHarvard universityShira weingarten gabbayPardis sabetiHasahn conwayMohsan saeedSchool of medicineNational institute of healthNational cancer instituteRagon instituteNational institute of allergyCancer research institute hearstBawd foundationLeadership program fellowshipMicrobiome program

Fundamental mechanism discovered that fine-tunes gene expression & is disrupted in cancer

Credit: The Wistar Institute PHILADELPHIA and MELBOURNE, Australia (May. 17, 2021) A team of scientists from The Wistar Institute in Philadelphia and the Peter MacCallum Cancer Center in Melbourne, Australia, discovered a new checkpoint mechanism that fine-tunes gene transcription. As reported in a study published in Cell, a component of the Integrator protein complex tethers the protein phosphatase 2A (PP2A) to the site of transcription allowing it to stop the activity of the RNA polymerase II enzyme (RNAPII). Disruption of this mechanism leads to unrestricted gene transcription and is implicated in cancer. The study points to new viable opportunities for therapeutic intervention demonstrating the anti-cancer effect of a new combination treatment in preclinical models of solid and hematopoietic malignancies.

New yorkUnited statesDana farber cancer instituteNew south walesBenjamin blythOtto kaukoJenniferr devlinSaraha welshElisa barbieriKaylenej simpsonEdwind hawkinsMichael ohlmeyerDeboraha knightMatteo costacurtaStefan bjelosevicGareth gregory