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Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults.

United statesUniversity of pennsylvaniaPeng xuYong chengLance palmerPeng huangKalin mayberryEmily hendersonRuopeng fengMitchellj weissThiyagaraj mayuranathanM celeste simonChunliang liGerda blobelPhillipa doerflerYu yao

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

New jerseyUnited statesJinchuan xingYong chengYeting zhangQian qiRuiqiong wuDewan shresthaEmily hendersonXing tangHuman genetics institute of new jerseyNational cancer instituteJude children research hospitalNational institutes of healthUniversity of tennessee health science centerUniversity of new jersey

St Jude finds new way to identify safe harbor for gene therapies

St Jude finds new way to identify safe harbor for gene therapies
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

New jerseyUnited statesJinchuan xingYong chengYeting zhangQian qiRuiqiong wuDewan shresthaXing tangRuiqiong rick wuHuman genetics institute of new jerseyNational cancer instituteJude children research hospitalNational institutes of healthUniversity of tennessee health science centerUniversity of new jersey

Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer

Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Yiannis drososTaosheng chenCharles robertsEmma beaneMargaret larsenSanthosh upadhyayaNatarajan bhanuCharles wm robertsSandi radko juettnerJacquelyn myersBaranda hansenSandeep dhandaRobert mobleyJanet partridgeXiaotu maBenjamin garcia

Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children.

Yiannis drososTaosheng chenEmma beaneMargaret larsenEmily hendersonSanthosh upadhyayaNatarajan bhanuCharles wm robertsSandi radko juettnerJacquelyn myersBaranda hansenSandeep dhandaRobert mobleyJanet partridgeXiaotu maBenjamin garcia