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Base editing shows potential superiority for

Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease. Find how St. Jude & Broad are advancing to a cure.

United statesYong chengYoonjeong jangJingjing chenYu yaoRachel levineSenthil velan bhoopalanRuopeng fengMitchell weissDavid liuJohn tisdaleYichao liShondra pruett millerAkshay sharmaHenry bellThiyagaraj mayuranathan

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

United statesLily ramseySenthil velan bhoopalanCicera lazzarottoGuolian kangYong chengPhillip doerflerErin dempseyMitchell weissGregory newbyRuopeng fengYu yaoRachel levineJingjing zhangShengdar tsaiHenry bell

Research Roundup: Findings in Sickle Cell Disease, Alzheimer s, Allergic Asthma and More

This week, new research is presented in treatments for sickle cell disease, Alzheimer's, asthma, and type 1 diabetes. Here's a look at that and more.

Ruopeng fengStefan feskeLangone healthGrossman school of medicineResearch gettystockJude children research hospitalDepartment of pathologySickle cellJude childrenResearch hospitalNerve growth factorAllergic asthmaWeakening defensesJeffrey bergstein professorEsearch roundup findings in sickle cell diseaseAlzheimer 39 s

A link between hypoxia and fetal hemoglobin provides hope for sickle cell disease

Cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for some genetic anemias.

Mitchellj weissRuopeng fengJude children research hospitalJude hematology departmentJude childrenResearch hospitalSickle cellFetal hemoglobin

Link between hypoxia and fetal hemoglobin provides hope for sickle cell disease

Link between hypoxia and fetal hemoglobin provides hope for sickle cell disease
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United statesUniversity of pennsylvaniaPeng xuYong chengLance palmerPeng huangKalin mayberryRuopeng fengMitchellj weissThiyagaraj mayuranathanM celeste simonChunliang liGerda blobelPhillipa doerflerYu yaoJingjing zhang

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