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Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer

Strategy overcomes EZH2 inhibitor resistance in SMARCB1 mutated cancer
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Novel drug target may help overcome resistance to EZH2 inhibitors in SMARCB1 mutated cancers

Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children.

Yiannis drososTaosheng chenEmma beaneMargaret larsenEmily hendersonSanthosh upadhyayaNatarajan bhanuCharles wm robertsSandi radko juettnerJacquelyn myersBaranda hansenSandeep dhandaRobert mobleyJanet partridgeXiaotu maBenjamin garcia