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Ruxolitinib in Chronic GVHD

The expert panel explores the approval of ruxolitinib for chronic GVHD based on the REACH3 trial. The panel highlights the trial’s outcomes, long-term follow-up data, and the evolving shift in clinical practices.

Dana farber cancer instituteUnited statesBin chenCorey cutlerMitchell horwitzRobert zeiserHannah choeProfessor of medicine at harvard medical schoolCell therapy program at massachusettsOhio state universityMarrow transplant program at duke universityCell therapy programMassachusetts general hospitalHarvard medical schoolStem cell transplant programAdult blood

Treatment Strategies for Managing BTK Inhibitor Intolerance in CLL

Richard Furman, MD, outlines his strategy for addressing BTK inhibitor intolerance in CLL patients, underscoring the significance of BTK inhibitors in CLL treatment and advocating for transitioning to an alternative BTK inhibitor rather than completely discontinuing the class in cases of drug intolerance.

Chaitras ujjaniRichard furmanNews networkChronic lymphocytic leukemiaContinuous btki therapyFixed duration therapyTumor lysis monitoringElevate tnMash 2023Elevate rrTreatment naïve cllNewly diagnosed cllRelapsed cllRefractory cllReal world dataTreatment resistance

#VisualAbstract: Chronic Lymphocytic Leukemia (CLL) therapy with Ibrutinib and Venetoclax guided by measurable residual disease improves progression-free survival

Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Minute medicine incChronic lymphocytic leukemiaIbrutinib venetoclaxMinimal residual diseasePersonalized therapy

Unmet Needs In CLL and SLL Treatment Management

Deborah Stephens, DO, shares unmet needs in the current treatment landscape of CLL and SLL.

Bryan jacobsJennifer woyachDeborah stephensTara graffRyan haumschildPeer exchangeBtk inhibition in cll sllBtk inhibitors efficacyCll sll managementB cell receptor signalingBtk inhibitors advantagesBtk inhibitors in hematologyCll sll treatment advancements

Evaluating Current Treatment Landscape of CLL and SLL

A panel of experts explore current treatment strategies in CLL and SLL management.

Bryan jacobsJennifer woyachDeborah stephensTara graffRyan haumschildPeer exchangeProgression free survivalBtk inhibitors

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