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Ironwood Pharmaceuticals Announces Positive Results from its Phase II Exploratory STARGAZE Trial of Apraglutide in Patients with Steroid-Refractory Gastrointestinal Acute Graft-versus-Host Disease (SR GI aGVHD)

Ironwood Pharmaceuticals Announces Positive Results from its Phase II Exploratory STARGAZE Trial of Apraglutide in Patients with Steroid-Refractory Gastrointestinal Acute Graft-versus-Host Disease (SR GI aGVHD)
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United statesMichael shetzlineRobert zeiserIronwood pharmaceuticalsInternational consortiumExchange commissionUniversity of freiburgIronwood pharmaceuticals nasdaqIronwood pharmaceuticals incHead of researchGraft versus host diseaseMount sinai acutePrincipal investigatorSenior vice presidentChief medical officerAcute graft versus host disease

Ironwood Pharma (IRWD) Announces Positive Results from its Phase II Exploratory STARGAZE Trial of Apraglutide in Patients with Steroid-Refractory Gastrointestinal Acute Graft-versus-Host Disease

Ironwood Pharma (IRWD) Announces Positive Results from its Phase II Exploratory STARGAZE Trial of Apraglutide in Patients with Steroid-Refractory Gastrointestinal Acute Graft-versus-Host Disease
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Robert zeiserMichael shetzlineInternational consortiumHead of researchUniversity of freiburgIronwood pharmaceuticalsIronwood pharmaceuticals inc nasdaqGraft versus host diseaseMount sinai acutePrincipal investigatorSenior vice presidentChief medical officer

Ironwood spies new frontier for $1B drug in exploratory trial

Ironwood spies new frontier for $1B drug in exploratory trial
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Incyte jakafiRobert zeiserIronwood pharmaceuticalUniversity of freiburg

Ruxolitinib in Chronic GVHD

The expert panel explores the approval of ruxolitinib for chronic GVHD based on the REACH3 trial. The panel highlights the trial’s outcomes, long-term follow-up data, and the evolving shift in clinical practices.

Dana farber cancer instituteUnited statesBin chenCorey cutlerMitchell horwitzRobert zeiserHannah choeProfessor of medicine at harvard medical schoolCell therapy program at massachusettsOhio state universityMarrow transplant program at duke universityCell therapy programMassachusetts general hospitalHarvard medical schoolStem cell transplant programAdult blood

Jakafi Results in Improved Control of Steroid Refractor/Dependent cGVHD

The three-year final analysis of efficacy and safety of the REACH3 trial showed that patients with steroid-refractory or dependent chronic graft-versus-host disease benefited more with Jakafi compared with the best available treatment.

Robert zeiserCenter at university of freiburgMedical centerBlood cancerAmerican society of hematology