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Expert Perspectives on Extended Follow-Up Data from ALPINE

CLL Society s Koffman Says ASH 2023 Offered Evolutionary Changes

Extended Follow-up of ALPINE Randomized Phase 3 Study Confirms Sustained Superior Progression-free Survival of Zanubrutinib Versus Ibrutinib for Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (R/R CLL/SLL)

Zanubrutinib Continues to Derive PFS Benefit Vs Ibrutinib in Relapsed/Refractory CLL/SLL

Jennifer R. Brown, MD, PhD, discusses the clinical implications of the ALPINE study and highlights a subgroup analysis of acquired mutations in patients with chronic lymphocytic leukemia, demonstrating which mutations were associated with resistance to covalent BTK inhibitors.

#VisualAbstract: Ibrutinib-Venetoclax Improves Progression-Free Survival in Chronic Lymphocytic Leukemia

Click here to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

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