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Shape-shifting immune cells offer new insights into cancer immunotherapy

Shape-shifting immune cells offer new insights into cancer immunotherapy
harvard.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from harvard.edu Daily Mail and Mail on Sunday newspapers.

Samir mitragotriKolade adebowaleJennifer guerrieroMitragotri laboratory for drug delivery harvardNational science foundation under award noProfessor at harvard medical schoolHarvard johna paulson school of engineeringWomen hospital breast oncology programMitragotri laboratoryHarvard johnApplied sciencesHiller professorHansjorg wyss professorBiologically inspired engineeringApplied physicsAssistant professor

Using the body s own cells to treat traumatic brain injury

Using the body s own cells to treat traumatic brain injury
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United statesNeha kapateDonald ingberRick liaoSamir mitragotriWyss institute at harvard universityWyss instituteCore facultyHarvard universityHiller professorWyss professorBiologically inspired engineeringApplied sciencesPostdoctoral fellowMass general hospitalWyss founding director donald ingber

Shining a light on the hidden damage of mild

<p>We all know someone who's had a head injury that was "only" a concussion, but even mild traumatic brain injuries can cause lasting damage, and the vast majority are never diagnosed. A team led by Samir Mitragotri at the Wyss Institute, Harvard SEAS, and Boston Children's Hospital created a way to diagnose mild TBIs (mTBIs) even when MRI scans showed nothing, using the body's own immune cells called macrophages. They attached microparticle "backpacks" containing a common MRI contrast agent to the cells, which migrated to the brain and allowed them to see evidence of inflammation in pigs with a mock mTBI.</p>

United statesMichael dunneSuyong shahaSamir mitragotriLily li wen wangRebekah mannixRick liaoNeha kapateNinad kumbhojkarBolu ilelaboyeAndrew luTao sunJohn cleggYongsheng gaoMorgan janesVineeth chandran suja

New approach leverages macrophages to treat traumatic brain injury

Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs.

United statesRick liaoBeth costine bartellRohan rajeevSuyog shahaBryan golembNeha kapateKolade adebowaleLuke sodemannMorgan jamesSupriya prakashDonald ingberDania villafuerteVineeth chandran sujaNinad kumbhojkarMichael dunne

Using the body s own cells to treat traumatic

<p>Traumatic brain injuries (TBIs) can cause lasting damage, but stopping the rampant brain inflammation they cause is difficult. A team at the Wyss, @SEAS and @MGH led by Samir Mitragotri has made a new treatment using macrophages - immune cells that migrate to the brain. By attaching microparticle "backpacks" that kept the macrophages in a healing state, they reduced the size of brain lesions by 56% in pigs with a mock TBI.</p>

United statesDania villafuerteMikayla flanzDonald ingberKolade adebowaleSupriya prakashBryan golembMorgan jamesDeclan mcguoneBeth costine bartellVineeth chandran sujaJohn cleggNinad kumbhojkarSuyog shahaRick liaoNeha kapate