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SCALAR: A microchip designed to transform the production of mRNA therapeutics and vaccines

SCALAR: A microchip designed to transform the production of mRNA therapeutics and vaccines
upenn.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from upenn.edu Daily Mail and Mail on Sunday newspapers.

Peek into an afternoon at Penn s collaborative bioengineering lab and makerspace

The space offers a variety of tools and resources for the university's community, whether they are enrolled in the bioengineering department and taking a class in the laboratory or not.

Recipients Selected for the American Brain Foundation 2022 Cure One, Cure Many Award for the Early Diagnosis of Lewy Body Dementia

New microfluidic device delivers mRNA nanoparticles a hundred times faster

With a ‘liquid assembly line,’ Penn researchers have produced mRNA-delivering-nanoparticles significantly faster than standard microfluidic technologies. The COVID vaccines currently being deployed were developed with unprecedented speed, but the mRNA technology at work in some of them is an equally impressive success story. Because any desired mRNA sequence can be synthesized in massive quantities, one of the biggest hurdles in a variety of mRNA therapies is the ability to package those sequences into the lipid nanoparticles that deliver them into cells. The researchers’ new platform technology, called Very Large Scale Microfluidic Integration, allows tens of thousands of microfluidic units to be incorporated into a single three-dimensionally etched silicon-and-glass wafer. (Image: Penn Engineering Today)

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