The configuration of brown and white stripes in pygmy zebra octopuses (Octopus chierchiae) varies between individuals, which could help researchers monitor them in the wild
There is no escaping the baby formula shortages, with pharmacies in Richmond reporting that shelves are becoming increasingly bare of the much-needed food supply.
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SARS-CoV-2 suppresses host innate immunity
SARS-CoV-2, the virus that causes COVID-19, blocks the processes of innate immune activation that normally direct the production and/or signaling of type I interferon (IFN-I) by the infected cell and tissues. IFN-I is a key component of host innate immunity that is responsible for eliminating the virus at the early stage of infection, as summarized in a recent review article in
Journal of Interferon & Cytokine Research (JICR). By suppressing innate immunity, the virus replicates and spreads in the body unchecked, leading to the disease known as COVID-19.
SARS-CoV-2 utilizes various approaches to evade host IFN-I response, including suppression of IFN-I production and IFN-I signaling. Viruses defective in antagonizing IFN-I response, in combination with replication-defective mutations, could potentially be developed as live attenuated vaccine candidates.