Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

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Pauline Wimberger ,Anneline Pinson ,Wieland Huttner ,Emily Henderson ,Max Planck Institute Of Molecular Cell Biology ,University Hospital Dresden ,Max Planck Institute ,Molecular Cell Biology ,Evolutionary Anthropology ,Brain ,Eurons ,Amino Acid ,Arginine ,Fell ,Cell Biology ,Revolution ,Enetics ,Glial Cell ,Ysine ,Icroscopy ,Neocortex ,Euron ,Progenitor Cells ,Protein ,Research ,