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Human evolution: A single gene mutation may have made us smarter than Neanderthals

Modern humans have a gene mutation that boosts the growth of neurons in the brain neocortex, a brain region associated with higher intelligence

Anneline pinsonWieland huttnerMax planck institute of molecular cell biologyMax planck instituteMolecular cell biology

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

Pauline wimbergerAnneline pinsonWieland huttnerEmily hendersonMax planck institute of molecular cell biologyUniversity hospital dresdenMax planck instituteMolecular cell biologyEvolutionary anthropologyAmino acidCell biologyGlial cellProgenitor cells

Modern humans generate more brain neurons than Neanderthals – Popular Archeology

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

Pauline wimbergerAnneline pinsonWieland huttnerMax planck institute of molecular cell biologyUniversity hospital dresdenMax planck instituteMolecular cell biologyEvolutionary anthropologyTop leftDigital artist

A single genomic change may have given modern humans an advantage over Neanderthals

A single amino acid change in the transketolase-like 1 (TKTL1) protein may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, researchers report.

Laurent nguyenBrigitte malgrangeAnneline pinsonEmily hendersonAmino acid

Neocortical Neurogenesis in Modern Humans Greater Than It Was in Neanderthals

Neocortical Neurogenesis in Modern Humans Greater Than It Was in Neanderthals
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Anneline pinsonWieland huttnerMax planck institute of molecular cell biologyNeanderthal museumMax planck instituteMolecular cell biologyProfessor wieland huttner

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