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Seelos Therapeutics, Inc. a clinical-stage biopharmaceutical company focused on the development of therapies for central nervous system disorders and rare diseases, today announced that the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital has selected Seelos’ Phase IIbIII study of SLS-005 to be included in the HEALEY ALS Platform Trial, the first ever platform trial for the treatment of … – Seelos Therapeutics, Inc. (Nasdaq: SEEL), a clinical-stage biopharmaceutical company focused on the development of therapies for central nervous system disorders and rare diseases, today announced that the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital has selected Seelos’ Phase IIbIII study of SLS-005 (trehalose) to be included in the HEALEY ALS Platform Trial, the first ever platform trial for the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease). ....
Target ALS Announces Second Round of 2020 Grant Recipients Focused on Discovering and Developing ALS Biomarkers Share Article The Target ALS Diagnosis Initiative We are now at a juncture where reliable biomarkers are an increasingly acute need. We look forward to the contribution of these consortia in this search, which could greatly improve the lives of ALS patients. NEW YORK (PRWEB) December 15, 2020 Target ALS announced today the grantees receiving funding for new projects focused on ALS biomarker discovery and development, resulting from a call for proposals issued in the spring. In accordance with the requirements of the Target ALS grantmaking process, collaboration between academic investigators and the pharma/biotech industry was required to apply. This funding builds on $5 million in grants awarded to projects earlier this year, in collaboration with The Association for Frontotemporal ....
Updated Dec 14, 2020 | 11:13 IST A study suggests that the antiepileptic drug ezogabine reduced pathologic excitability of cortical and spinal motor neuron cells that are early signs of clinical dysfunction in people with ALS. Consuming the antiepileptic drug in ALS can reduce motor neuron excitability | Photo Credit: Pixabay Washington: A new study suggests that the antiepileptic drug ezogabine reduced pathologic excitability of cortical and spinal motor neuron cells that are early signs of clinical dysfunction in people with amyotrophic lateral sclerosis (ALS). The study was conducted by the Neurological Clinical Research Institute of Massachusetts General Hospital (MGH). In addition to providing a clearer understanding of motor neuron excitability as an important disease pathway for ALS, the multi-site study, published in JAMA Neurology, involves the first clinical investigation of ALS (also known as Lou Gehrig s disease) using a drug ....
Antiepileptic drug can reduce motor neuron excitability bostonstar.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bostonstar.com Daily Mail and Mail on Sunday newspapers.
Consuming antiepileptic drug in ALS can reduce motor neuron excitability ANI | Updated: Dec 13, 2020 18:19 IST Washington [US], December 13 (ANI): A new study suggests that the drug-ezogabine >drug >antiepileptic drug ezogabine reduced pathologic excitability of cortical and spinal motor neuron cells that are early signs of clinical dysfunction in people with amyotrophic lateral sclerosis (ALS). The study was conducted by the Neurological Clinical Research Institute of Massachusetts General Hospital (MGH). In addition to providing a clearer understanding of motor neuron excitability as an important disease pathway for ALS, the multi-site study, published in JAMA Neurology, involves the first clinical investigation of ALS (also known as Lou Gehrig s disease) using a drug identified through an induced pluripotent stem cell (iPSC) model. ....