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Apixaban Curbs Subclinical Thrombosis After TAVI in Patients Without Prior OAC

May 17, 2021
Use of apixaban (Eliquis; Bristol-Myers Squibb) following transcatheter aortic valve implantation does not significantly reduce the risk of subclinical valve thrombosis when compared with standard of care, according to a CT substudy from the ATLANTIS trial presented today.
However, the results are nuanced, with investigators reporting an intriguing interaction between thrombus risk and prior oral anticoagulation indication. For patients without an indication for oral anticoagulation, use of apixaban as opposed to antiplatelet therapy was associated with a lower risk of subclinical valve thrombosis as measured by reduced leaflet motion (RLM) and hypoattenuated leaflet thickening (HALT).
By contrast, for those with an indication for oral anticoagulation, apixaban failed to prevent subclinical valve thrombosis when compared with a vitamin K antagonist. ....

France General , Gilles Montalescot , Andrew Goldsweig , Adnan Chhatriwalla , Baylor Scott White , Joao Cavalcante , Bristol Myers Squibb , Michael Mack , David Cohen , American College Of Cardiology , Phd Centre Hospitalier Universitaire Piti , Md University Of Nebraska Medical Center , Heart Center , Md Saint Luke Mid America Heart Institute , Md Minneapolis Heart Institute , American College , Centre Hospitalier Universitaire Piti , Francis Hospital , Evolut Low Risk Trial , Nebraska Medical Center , Baylor Scott , White Heart Hospital , Minneapolis Heart Institute , Saint Luke , Mid America Heart Institute , Kansas City ,

ATLANTIS: Apixaban Has No Benefit Over Standard of Care Post-TAVI

Future research needs to consider the longer-term impact of thrombus and whether certain patient subsets could benefit. ....

France General , Baylor Scott , Michael Mack , Jean Philippe Collet , Bayer Janssen , American College Of Cardiology , Md Morristown Medical Center , American College , Morristown Medical Center , Treat Analysis , Significant Clinical , White Heart Hospital , பிரான்ஸ் ஜநரல் , பேலர் ஸ்காட் , மைக்கேல் மேக் , ஜீன் பிலிப் கோலட் , பேயர் ஜான்சன் , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் , ம்ட் மோரிஸ்டவுன் மருத்துவ மையம் , அமெரிக்கன் கல்லூரி , மோரிஸ்டவுன் மருத்துவ மையம் , உபசரிப்பு பகுப்பாய்வு , வெள்ளை இதயம் மருத்துவமனை ,

Beloved Wichita Falls doctor beats COVID-19 after 105 days in hospital

Surrounded by family and close friends, Dr. Rodrigo Menchaca waved and thanked the well-wishers participating in a drive-by welcome home event Saturday at the MPEC parking lot.
Honking horns, ringing cowbells and holding signs, they poured out their love for a man who has touched countless lives, and saved many of them over the years.
Menchaca has been an emergency room physician for 35 years at United Regional Health Care System.
He has returned home after a long battle with COVID-19. In all, he was hospitalized for 105 days and 46 of those were on a ventilator.
One of the people in the long line of cars asked how he was doing. I m doing great, thanks to all the prayers you guys sent up to Heaven, replied Menchaca. ....

Baylor Scott , Rodrigo Menchaca , Teresa Menchaca , United Regional Health Care System , United Regional Health Care , Wichita Falls , White Heart Hospital , பேலர் ஸ்காட் , ரோட்ரிகோ மேன்சக , தெரசா மேன்சக , ஒன்றுபட்டது பிராந்திய ஆரோக்கியம் பராமரிப்பு அமைப்பு , ஒன்றுபட்டது பிராந்திய ஆரோக்கியம் பராமரிப்பு , விசிட்டா விழும் , வெள்ளை இதயம் மருத்துவமனை ,

Jeffrey R. Gladden, MD, FACC is recognized by Continental Who's Who

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DALLAS, Feb. 8, 2021 /PRNewswire/ Jeffrey R. Gladden, MD, FACC, is being recognized by Continental Who s Who as a Top Health, Longevity, and Human Performance Optimization Physician for his outstanding contributions in the field of Longevity Medicine. Gladden Longevity is devoted to the Optimization of Health, Longevity, and Human Performance. Offices are located in Dallas, Texas.
(PRNewsfoto/Continental Who s Who)
Dr. Gladden brings over 25 years of professional excellence as an Interventional Cardiologist. He started his own cardiology group and grew it to ten offices and a dozen cardiologists. In addition, he co-founded the Baylor Scott and White Heart Hospital in Plano, as well as several Cardiac Catherization programs at hospitals surrounding Dallas. He is also involved in several medical startups and is currently active on two of their boards. ....

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