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E-Mail IMAGE: Charu Aggarwal, MD, MPH (top), Ronac Mamtani, MD, (bottom left), and Lova Sun, MD. view more Credit: Penn Medicine PHILADELPHIA Real-word evidence is suggesting, for the first time, the most beneficial treatment courses that could help extend the lives of patients with metastatic non-small cell lung cancer, according to research from the Abramson Cancer Center at the University of Pennsylvania. In a new study published online today in JAMA Oncology, researchers show that patients harboring a KRAS gene mutation with high levels of PDL-1 lived longer when treated with immunotherapy alone, compared to patients without this mutation. This survival difference by KRAS status was not seen, however, in patients treated with both chemotherapy and immunotherapy, suggesting combination therapy for patients without the mutation may be preferred. ....
Even Patients With Cancer in Remission at Risk for Severe COVID medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.
E-Mail PHILADELPHIA Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in JNCI Cancer Spectrum shows. Past reports have established an increased risk of severe disease and death for sick or hospitalized cancer patients with COVID-19 compared to patients without cancer, but less is known about patients in the general population. The findings underscore the importance of COVID-19 mitigation, like social distancing and mask wearing, and vaccinations for all patients, not just those recently diagnosed or with active disease. Patients who have cancer need to be careful not to become exposed during this time, said senior author ....